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If choosing one time, evening application may be slightly more effective for wrinkle treatment since skin repair processes increase during sleep

Those prioritizing convenience may simply rotate through standard sites without concern for proximity to target fat areas

The challenge is getting it into cells via supplementation

In a landmark study published in the Journal of Investigative Dermatology , researchers found that GHK-Cu was more effective than vitamin C and retinoic acid in stimulating collagen production in aged human skin